| Product name |
4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-3,5-difluoro-4′-(trans-4-propylcyclohexyl)-1,1′-biphenyl |
| CAS NO. |
303186-22-3 |
| Purity |
95% min |
Frequently Asked Questions：
Q1: What is the CAS number and molecular formula of this product?
The CAS Registry Number is 303186-22-3. The molecular formula is C₂₈H₂₅F₇O with a molecular weight of 510.49 g/mol. It is a heptafluoro-substituted biphenyl derivative featuring a trans-4-propylcyclohexyl terminal group and a difluoro(difluorophenoxy)methyl bridging group.
Q2: What are the physical properties of this compound?
The compound appears as a white crystalline solid. Standard purity is 95% min by GC, with ≥99% available upon request. The predicted boiling point is approximately 513 °C and the predicted density is 1.252 g/cm³. It is soluble in common organic solvents such as chloroform and slightly soluble in methanol.
Q3: What are the main applications of CAS 303186-22-3?
This compound is primarily used as:
• A key intermediate for VA-mode (Vertical Alignment) liquid crystal mixtures, leveraging its negative dielectric anisotropy from 2,3-difluoro substitution
• A low-viscosity diluent in high-refresh-rate TFT-LCD formulations, reducing rotational viscosity by 10–15%
• A precursor for OLED electron-transport and host materials, where fluorination lowers LUMO energy levels
Q4: How does the fluorine substitution pattern affect liquid crystal performance?
The 2,3-difluoro substitution on the biphenyl ring generates a strong transverse dipole moment, producing negative dielectric anisotropy (Δε ≈ −3 to −6) essential for VA-mode displays. The additional fluorine atoms on the phenoxy ether bridge (trifluorophenoxy group) further enhance resistivity and chemical stability. Together, the seven fluorine atoms deliver VHR > 99%, UV stability, and a broad nematic operating range from −30 °C to over 85 °C.
Q5: What packaging options are available?
Standard packaging includes fluoride bottles, fluoride drums, iron drums, plastic drums, or IBC tanks. Custom packaging is available upon request for sample quantities (1 g, 5 g, 25 g) or bulk orders.
Application Cases：
Case 1: VA-Mode LCD Panel for High-End Television
This compound was incorporated at 8–15 wt% into a VA-mode nematic LC host mixture to improve contrast ratio and eliminate image sticking. Its 2,3-difluoro substitution provided negative dielectric anisotropy (Δε ≈ −4.5), while the heptafluoro structure delivered resistivity exceeding 10¹² Ω·cm. The optimized panel achieved a static contrast ratio of 6000:1 and VHR > 99.5% after 1000 hours of continuous operation, meeting premium TV display standards.
Case 2: High-Refresh-Rate Gaming Monitor LC Formulation
Used as a low-viscosity diluent at 10–20 wt% in a gaming monitor LC formulation, this compound reduced the mixture’s rotational viscosity from >30 mPa·s to below 20 mPa·s through its lateral fluorine substitution. The reformulated mixture achieved a gray-to-gray response time of 7.2 ms and maintained a virtual clearing point above 125 °C, supporting 144 Hz and 240 Hz refresh rate displays.
Case 3: Automotive Display with Wide Temperature Range Operation
Incorporated at 12 wt% for automotive instrument cluster displays, this compound enabled reliable operation from −30 °C to 85 °C. Its heptafluoro structure suppressed crystallization and the trans-4-propylcyclohexyl group optimized molecular aspect ratio for nematic stability. The display maintained response time < 15 ms at −30 °C and passed 2000 hours of AEC-Q100 Grade 2 reliability testing with optical deviation < 3%.
Case 4: OLED Electron-Transport Layer Material Development
The heptafluoro-substituted biphenyl structure was used as a key building block for synthesizing an n-type OLED host material. The seven fluorine atoms lowered the LUMO energy level by approximately 0.3 eV compared to the non-fluorinated analogue, facilitating electron injection. The resulting green phosphorescent OLED device achieved EQE of 18.2% and operational half-lifetime (LT50) exceeding 50,000 hours at 1000 cd/m².
Case 5: IPS/FFS Mobile Display with Low Power Consumption
At 6–10 wt% in an IPS LC formulation, this compound enabled a 16% reduction in power consumption through its negative dielectric anisotropy (Δε ≈ −4.0) and high resistivity. The moderate birefringence (Δn ≈ 0.11) allowed thinner cell gap design from 3.5 μm to 3.0 μm, dropping threshold voltage from 1.8 V to 1.5 V while maintaining response time < 8 ms and off-axis contrast improvement of 12% at 80° viewing angle.
