| CAS NO.442912-77-8 4′-(trans-4-Ethylcyclohexyl)-2,3-difluoro-4-propoxy-1,1′-biphenyl | |
| Product Name | 4′-(trans-4-Ethylcyclohexyl)-2,3-difluoro-4-propoxy-1,1′-biphenyl |
| Synonyms | 2,3-Difluoro-4-propoxy-4′-(trans-4-ethylcyclohexyl)-1,1′-biphenyl; 4-Propoxy-2,3-difluoro-4′-(trans-4-ethylcyclohexyl)biphenyl |
| CAS NO. | 442912-77-8 |
| Appearance | White solid |
| Purity | 95% min |
| MF | C23H28F2O |
| MW | 358.47 |
| Storage | Preserve in a well-closed container and keep in cool, dry place, avoid light. |
| Package | In fluoride bottle/ Fluoride drums/iron drums/plastic drums/IBC Tank ,etc. |
| Shipment method | By Sea, Air, Courier door to door, etc. |
| Loading Port | China any port, Beijing, Shanghai, Hong Kong etc. |
| Application | 1. Nematic Liquid Crystal Mixtures for TFT-LCD Displays As a fluorinated biphenyl derivative with a trans-4-ethylcyclohexyl terminal group, this compound contributes to nematic liquid crystal mixtures used in TFT-LCD panels. The 2,3-difluoro substitution on the biphenyl core reduces rotational viscosity while the propoxy group and ethylcyclohexyl terminal provide structural balance between rigidity and flexibility, supporting fast electro-optical response required for high-resolution display applications.
2. Low-Viscosity LC Formulation Component The trans-4-ethylcyclohexyl terminal group represents one of the shortest alkyl-substituted cyclohexyl moieties commonly used in fluorinated biphenyl liquid crystals. Compared to propyl or butyl cyclohexyl homologs, the ethyl variant contributes to lower rotational viscosity in the overall mixture, making this compound particularly valuable in LC formulations that require fast switching speeds for video-rate and high-refresh-rate display applications. 3. Wide-Temperature Nematic Mixture Design The rigid biphenyl core with 2,3-difluoro substitution provides high optical anisotropy (birefringence) and good clearing temperature. Combined with the flexible propoxy chain and ethylcyclohexyl terminal, this compound helps maintain a wide nematic phase temperature range, ensuring reliable liquid crystal operation across both high and low temperature extremes in outdoor and industrial display applications. 4. IPS and FFS Mode Display Components In in-plane switching (IPS) and fringe-field switching (FFS) display modes, the dielectric and elastic properties of individual components are critical. The fluorinated biphenyl structure of this compound provides moderate dielectric anisotropy and favorable elastic constant ratios that contribute to stable director alignment under lateral electric fields, supporting the wide viewing angle performance characteristic of IPS and FFS display panels. 5. Advanced Display Materials for High-Resolution Panels As display technology advances toward higher resolutions (4K, 8K) and faster response times, the demand for liquid crystal materials with precisely controlled viscosity, birefringence, and dielectric properties increases. This compound serves as a specialized component in multi-component LC mixtures designed for next-generation display panels, where its specific molecular architecture enables fine-tuning of the mixture’s electro-optical performance. |
| Contact | Contact person: James Zhang
Email: james.zhang@dakenchem.com |
Frequently Asked Questions
Q1: What is CAS NO.442912-77-8 and what is its chemical structure?
CAS NO.442912-77-8, or 4′-(trans-4-ethylcyclohexyl)-2,3-difluoro-4-propoxy-1,1′-biphenyl, is a fluorinated biphenyl liquid crystal compound with molecular formula C23H28F2O and molecular weight 358.47 g/mol. The molecule features a central biphenyl core with 2,3-difluoro substitution on one ring, a propoxy group at the 4-position, and a trans-4-ethylcyclohexyl terminal group at the 4′-position. This rod-like (calamitic) molecular geometry is characteristic of thermotropic nematic liquid crystal materials.
Q2: What role do the fluorine atoms play in this compound?
The two fluorine atoms at the 2,3-positions of the biphenyl core serve multiple functions. They reduce the rotational viscosity of the molecule by decreasing intermolecular interactions, contribute to the overall dielectric anisotropy, and help stabilize the nematic phase. Unlike in some other fluorinated liquid crystals where fluorine acts as a leaving group in cross-coupling reactions, here the fluorine atoms are integral structural elements that remain in the final molecule to modulate its electro-optical properties.
Q3: How does the ethylcyclohexyl terminal group affect performance?
The trans-4-ethylcyclohexyl group is one of the shortest alkyl-substituted cyclohexyl terminals used in this class of fluorinated biphenyl liquid crystals. Compared to propyl, butyl, or pentyl cyclohexyl homologs, the ethyl variant reduces rotational viscosity, enabling faster molecular reorientation under electric fields. This property is particularly beneficial for applications requiring rapid switching speeds, such as video-rate displays and high-refresh-rate panels.
Q4: What are the key physical and chemical properties?
The compound has a molecular weight of 358.47 g/mol and a predicted boiling point of approximately 435°C. The predicted density is approximately 1.04 g/cm³. It appears as a white solid at room temperature. The molecule is soluble in common organic solvents such as dichloromethane, THF, and toluene. The trans configuration of the ethylcyclohexyl group ensures a linear molecular shape essential for nematic phase formation.
Q5: What display technologies use this type of compound?
Fluorinated biphenyl derivatives like this compound are used as components in nematic liquid crystal mixtures for various display modes including: TFT-LCD (thin-film transistor liquid crystal display) panels; IPS (in-plane switching) and FFS (fringe-field switching) mode displays for wide viewing angles; and advanced high-resolution display panels requiring precise electro-optical performance control. The compound contributes to achieving the optimal balance of viscosity, birefringence, and dielectric properties.
Application Cases
Application Case 1: TFT-LCD Mixture for High-Resolution Panels
A liquid crystal materials manufacturer incorporated this fluorinated biphenyl compound into a multi-component nematic mixture designed for high-resolution TFT-LCD display panels. The compound’s 2,3-difluoro substitution contributed to reducing the overall rotational viscosity of the mixture, while the trans-4-ethylcyclohexyl terminal group provided additional viscosity reduction compared to longer-chain homologs. The resulting mixture achieved the fast response times required for 4K resolution display operation.
Application Case 2: Low-Viscosity Formulation for Fast Switching Displays
A display materials research team specifically selected this ethylcyclohexyl-substituted fluorinated biphenyl over its propyl and butyl homologs to minimize the rotational viscosity of their nematic formulation. The ethyl group being the shortest practical alkyl terminal on the cyclohexyl ring reduced intermolecular friction in the liquid crystal phase, enabling faster electro-optical switching suitable for high-refresh-rate gaming monitors and professional display applications.
Application Case 3: IPS Mode Display with Wide Viewing Angle
For an IPS-mode display formulation requiring stable director alignment under lateral electric fields, a formulator included this compound as a birefringence and elastic constant tuning component. The rigid fluorinated biphenyl core provided adequate optical anisotropy while the balanced molecular design ensured compatibility with other mixture components. The resulting display panel demonstrated consistent color reproduction across wide viewing angles.
Application Case 4: Wide-Temperature LC Mixture for Automotive Displays
An automotive display supplier developed a liquid crystal mixture requiring reliable operation from -40°C to over 100°C. This compound was included in the formulation because its fluorinated biphenyl structure contributed to a high clearing temperature, while the propoxy chain and ethylcyclohexyl terminal helped suppress the melting point, maintaining a wide nematic phase range. The mixture successfully passed automotive temperature cycling reliability tests.
Application Case 5: Optical Anisotropy Tuning in Custom Mixture
A specialty LC mixture supplier used this compound as an optical anisotropy tuning component in a custom nematic formulation for an industrial display application. By adjusting the proportion of this fluorinated biphenyl component relative to other mixture ingredients, the supplier achieved the target birefringence value (Δn) while maintaining acceptable viscosity and response time characteristics. The compound’s well-characterized electro-optical contribution enabled precise and reproducible formulation control.
